While black uses some generic discard effects to gain card advantage or punish certain strategies it is all about the targetted discard for disruption
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Aminatou, Veil Piercer Aminatou, Veil Piercer does some fun stuff with the miracles, either in its Miracle Worker EDH precon or in an Aminatou custom-built Commander deck
This one in particular should play well in many places
Brokers Confluence The Brokers from Streets of New Capenna were largely built with their shield counter mechanic in mind, so it makes sense to see proliferate on Brokers Confluence
As a player with ten or more poison counters on them loses the game, this greatly reduces the amount of damage an infect deck needs to deal in order to win a game