They wont have anything bad happen to them as a result
In matches where Ruby-based mirror matches end up passing back and forth, never playing more than one character at a time because you both have Be Prepared and the ink to pay wouldnt you rather have an Energy Blast
While it is a totally different game, the supercharger that the Terraforming Mars expansion Prelude offers gets that game up and running faster, without a hit to the gameplay
Playing an item early on means you might get to use it a few times, making it very valuable
If you reach the main event Day 2 or beyond, you just paid for the rest of the season of events
That is, until you take into account the cards first ability - The Power of Evil, which allows the player to play Chernabog, Evildoer for one less ink per character card they have in their discard