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Fmoc-Val-Ala-PAB(m-PEG8) Size:100mg 378 SMILES [N-]=[N+]=NCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

SKU: 80610052875

4.4
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Description

378 SMILES [N-]=[N+]=NCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

a novel and potent GSPT1 degrader displaying selectivity over 9000 proteins

85 SMILES: Cl

Product Name Biotin-PEG4-acid Synonyms CAS Number 721431-18-1 Related CAS Molecular Formula C21H37N3O8S Molecular Weight 491

Bioconjugate Chemistry

Fmoc-Val-Ala-PAB(m-PEG8) Size:100mg 378 SMILES [N-]=[N+]=NCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned

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