Fmoc-Val-Cit-PAB amine-amine The photostability and brightness of

The photostability and brightness of CPY make it a valuable tool for detailed imaging of cellular dynamics

The red-fluorescent 5-TAMRA alkyne is an excellent azide-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemitry

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C80H111FN12O27 Molecular Weight 1691

Contains an E3 ligase ligand with alkyl linker and a terminal piperazine moiety

96 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB amine-amine The photostability and brightness ofFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7