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Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan val Product Name HaXS8 Synonyms CAS

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Description

Product Name HaXS8 Synonyms CAS Number Related CAS Molecular Formula C35H43ClF4N6O8 Molecular Weight 787

Product Name Pomalidomide-CO-C5-Br Synonyms Pomalidomide-4'-CO-C5-Br CAS Number 2227423-38-1 Related CAS Molecular Formula C19H20BrN3O5 Molecular Weight 450

Product Name Thalidomide-O-PEG5-propargyl Synonyms Thalidomide-4'-O-PEG5-propargyl CAS Number 2411681-90-6 Related CAS Molecular Formula C26H32N2O10 Molecular Weight 532

89 SMILES ClCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO reacts with an azide group to form a stable triazole ring

Propargyl-Gly(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan val Product Name HaXS8 Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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