Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Sulfo-CA-Lissamine Rhodamine B is a

Sulfo-CA-Lissamine Rhodamine B is a sulfonated HaloTag substrate featuring a sulfonate group on the amide bond linking the chloroalkane moiety to the Lissamine Rhodamine B dye

peptides and proteins

Product Name Pomalidomide-C5-Br Synonyms Pomalidomide-4'-C5-Br CAS Number 2355289-70-0 Related CAS Molecular Formula C18H20BrN3O4 Molecular Weight 422

Product Name DOTA-tris(t-Bu)ester-PEG5-C2-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C47H83N7O15 Molecular Weight 986

275 (2024) paper studing DCAF1-based PROTACs

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Sulfo-CA-Lissamine Rhodamine B is aSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly