Thalidomide-O-PEG4-propargyl Size:25mg CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1 Purity (HPLC): ≥ 95%

CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

338 SMILES OCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The terminal alkyne group reacts with an azide to produce a stable triazole

thus all the instrument settings of the 6-ROX conjugates would be applicable to the applications of 6-ROX alkyne conjugates

227 SMILES [H]C(=O)NC1=CC=CC=C1C(=O)C[C@H](N)C(O)=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Thalidomide-O-PEG4-propargyl Size:25mg CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1 Purity (HPLC): ≥ 95%Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide O PEG4 propargyl Synonyms Thalidomide 4' O PEG4 propargyl CAS Number 2098799 77 8 Related CAS Molecular Formula C24H28N2O9 Molecular Weight 488. 493 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCCOCCOCCOCC#C)C=CC=C12