The chances of getting exactly what you want out of a set are very low, so buying singles may be the way to go if thats your goal
#10 Of all the Meld cards coming in The Brothers War, this is the easiest one to actually assemble
I can definitely imagine many Magic: the Gathering players will try to live the dream and assemble Mechtitan core, whether its in draft or Commander
Cards like Phyrexian Arena are also staples across formats, allowing you to have game against slower decks while slowly burying them in card advantage
While its not a time I care to commemorate much, I do have to point to a watershed moment in Magic history that came in 2020: the printing of cards based on other intellectual properties, in this case Entertainment Ones The Walking Dead
That should be more than enough to start over when your experiments aren't as successful as you might've hoped